With the continuous development of intelligent connected vehicle technology, multi-modal interaction technology is increasingly widely used in the field of autonomous driving. Therefore, this paper deeply studies the application of multimodal interaction technology in the automatic cockpit environment, focusing on speech, gesture, physiological perception and so on. At the same time, on the basis of in-depth analysis of the core challenges such as modal conflict and system robustness decline in the cabin, a system-level solution including modal decoupling structure, adaptive fault-tolerant mechanism and semantic discrimination priority strategy is proposed, hoping to promote the healthy development of intelligent connected vehicle industry, so that autonomous driving technology can better serve human society.